What is the point of no return in Mass Effect 3? Once the jump is made, the game is on rails until its conclusion. The hard point of no return in ME2 is passing through the Omega-4 Relay. Completing 4+ will have players finding the entire crew except for Dr. Once it’s installed, players must travel through the Omega 4 Relay immediately and start the suicide mission to rescue the whole crew of the Normandy and take out the Collectors Base.Ĭompleting 1-3 missions/assignments before passing through the relay will mean half of the crew dies. After this mission, players have until the Reaper IFF is installed to explore. During this mission’s events, the Normandy crew (non-squadmates) is abducted by the Collectors. The first is the Acquire Reaper IFF mission. Just like the first game, Mass Effect 2 has two different points of no return. What is the point of no return in Mass Effect 2?